The unique monoclonal antibodies and immunochemical assay for comprehensive determination of the cell-bound and soluble HER2 in different biological samples

Abstract The expression of the HER2 (human epidermal growth factor receptor 2) protein in cancer cells is a well-established cancer marker used for diagnostic and therapeutic purposes in modern treatment protocols, especially in breast cancer. The gold-standard immunohistochemical diagnostic methods...

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Bibliographic Details
Main Authors: Aleksandra Antos, Agnieszka Topolska-Woś, Marcin Woś, Agata Mitura, Paulina Sarzyńska, Tomasz Lipiński, Andrzej Kurylcio, Piotr Ziółkowski, Marta Świtalska, Joanna Tkaczuk-Włach, Andrzej Gamian, Wojciech P. Polkowski, Magdalena Staniszewska
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-54590-z