Teicoplanin derivatives block spike protein mediated viral entry as pan-SARS-CoV-2 inhibitors

Teicoplanin derivatives block spike protein mediated viral entry as pan-SARS-CoV-2 inhibitors

The rapid emergence of highly transmissible SARS-CoV-2 variants poses serious threat to the efficacy of vaccines and neutralizing antibodies. Thus, there is an urgent need to develop new and effective inhibitors against SARS-CoV-2 and future outbreaks. Here, we have identified a series of glycopepti...

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Bibliographic Details
Main Authors: Ling Ma, Yali Li, Ting Shi, Zhiling Zhu, Jianyuan zhao, Yongli Xie, Jiajia Wen, Saisai Guo, Jing Wang, Jiwei Ding, Chen Liang, Guangzhi Shan, Quanjie Li, Mei Ge, Shan Cen
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Biomedicine & Pharmacotherapy
Subjects:
SARS-CoV-2
Spike protein
Angiotensin converting enzyme 2
Teicoplanin
Entry inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222300001X

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http://www.sciencedirect.com/science/article/pii/S075333222300001X

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