Calibration methods to fit parameters within complex biological models

Mathematical and computational models of biological systems are increasingly complex, typically comprised of hybrid multi-scale methods such as ordinary differential equations, partial differential equations, agent-based and rule-based models, etc. These mechanistic models concurrently simulate deta...

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Bibliographic Details
Main Authors: Pariksheet Nanda, Denise E. Kirschner
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Applied Mathematics and Statistics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fams.2023.1256443/full