The vesicular stomatitis virus-based Ebola virus vaccine: From concept to clinical trials

The vesicular stomatitis virus-based Ebola virus vaccine: From concept to clinical trials

The devastating Ebola virus (EBOV) epidemic in West Africa in 2013–2016 accelerated the progress of several vaccines and antivirals through clinical trials, including the replication-competent vesicular stomatitis virus-based vaccine expressing the EBOV glycoprotein (VSV-EBOV). Extensive preclinical...

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Bibliographic Details
Main Authors: Ellen Suder, Wakako Furuyama, Heinz Feldmann, Andrea Marzi, Emmie de Wit
Format: Article
Language:English
Published: Taylor & Francis Group 2018-09-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
vsv-ebov
animal models
clinical trials
filovirus
preclinical testing
phase 1
phase 2
phase 3
Online Access:http://dx.doi.org/10.1080/21645515.2018.1473698

Internet

http://dx.doi.org/10.1080/21645515.2018.1473698

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