Cholestasis impairs gut microbiota development and bile salt hydrolase activity in preterm neonates

Cholestasis impairs gut microbiota development and bile salt hydrolase activity in preterm neonates

ABSTRACTCholestasis refers to impaired bile flow from the liver to the intestine. In neonates, cholestasis causes poor growth and may progress to liver failure and death. Normal bile flow requires an intact liver-gut-microbiome axis, whereby liver-derived primary bile acids are transformed into seco...

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Bibliographic Details
Main Authors: Lauren E. Lynch, Amy B. Hair, Krishnakant G. Soni, Heeju Yang, Laura A. Gollins, Monica Narvaez-Rivas, Kenneth D. R. Setchell, Geoffrey A. Preidis
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Gut Microbes
Subjects:
Microbiome
cholestasis
bile acids
neonate
growth
premature infant
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2023.2183690

Internet

https://www.tandfonline.com/doi/10.1080/19490976.2023.2183690

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