GdCl3 attenuates the glomerular sclerosis of streptozotocin (STZ) induced diabetic rats via inhibiting TGF-β/Smads signal pathway

GdCl3 attenuates the glomerular sclerosis of streptozotocin (STZ) induced diabetic rats via inhibiting TGF-β/Smads signal pathway

Diabetic nephropathy (DN) is the most serious end-stage renal disease which characterized by renal glomerular sclerosis including glomerular hypertrophy, glomerular basement membrane (GBM) thickening, mesangial expansion and renal fibrosis. TGF-β/Smads signal pathway plays a crucial role in the deve...

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Bibliographic Details
Main Authors: Jialin Li, Bing Wu, Haibo Hu, Xiansong Fang, Zhiping Liu, Suzhen Wu
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319341738

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http://www.sciencedirect.com/science/article/pii/S1347861319341738

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