Chromatin-Independent Interplay of NFATc1 and EZH2 in Pancreatic Cancer

Chromatin-Independent Interplay of NFATc1 and EZH2 in Pancreatic Cancer

Background: The Nuclear Factor of Activated T-cells 1 (NFATc1) transcription factor and the methyltransferase Enhancer of Zeste Homolog 2 (EZH2) significantly contribute to the aggressive phenotype of pancreatic ductal adenocarcinoma (PDAC). Herein, we aimed at dissecting the mechanistic background...

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Bibliographic Details
Main Authors: Shilpa Patil, Teresa Forster, Kristina Reutlinger, Waltraut Kopp, Lennart Versemann, Jessica Spitalieri, Jochen Gaedcke, Philipp Ströbel, Shiv K. Singh, Volker Ellenrieder, Albrecht Neesse, Elisabeth Hessmann
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Cells
Subjects:
chromatin
EZH2
NFATc1
pancreatic cancer
posttranslational EZH2 modification
Online Access:https://www.mdpi.com/2073-4409/10/12/3463

Internet

https://www.mdpi.com/2073-4409/10/12/3463

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