Stem cell-derived porcine macrophages as a new platform for studying host-pathogen interactions

Stem cell-derived porcine macrophages as a new platform for studying host-pathogen interactions

Abstract Background Infectious diseases of farmed and wild animals pose a recurrent threat to food security and human health. The macrophage, a key component of the innate immune system, is the first line of defence against many infectious agents and plays a major role in shaping the adaptive immune...

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Main Authors: Stephen Meek, Tom Watson, Lel Eory, Gus McFarlane, Felicity J. Wynne, Stephen McCleary, Laura E. M. Dunn, Emily M. Charlton, Chloe Craig, Barbara Shih, Tim Regan, Ryan Taylor, Linda Sutherland, Anton Gossner, Cosmin Chintoan-Uta, Sarah Fletcher, Philippa M. Beard, Musa A. Hassan, Finn Grey, Jayne C. Hope, Mark P. Stevens, Monika Nowak-Imialek, Heiner Niemann, Pablo J. Ross, Christine Tait-Burkard, Sarah M. Brown, Lucas Lefevre, Gerard Thomson, Barry W. McColl, Alistair B. Lawrence, Alan L. Archibald, Falko Steinbach, Helen R. Crooke, Xuefei Gao, Pentao Liu, Tom Burdon
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Biology
Subjects:
Pig
Pluripotent stem cell
Macrophage
PRRSV
ASFV
CRISPR
Online Access:https://doi.org/10.1186/s12915-021-01217-8

Internet

https://doi.org/10.1186/s12915-021-01217-8

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