An integrative pan cancer analysis of RET aberrations and their potential clinical implications

Abstract RET (rearranged during transfection), encoding a tyrosine kinase receptor, is a novel therapeutic target for cancers. The aberrations of RET are commonly found in cancers. Here, we profiled a comprehensive genomic landscape of RET mutations, copy number variants (CNVs), co-occurrence of RET...

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Bibliographic Details
Main Authors: Lei Zhou, Juanni Li, Xiaofang Zhang, Zhijie Xu, Yuanliang Yan, Kuan Hu
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-17791-y