SPECS: a non-parametric method to identify tissue-specific molecular features for unbalanced sample groups

SPECS: a non-parametric method to identify tissue-specific molecular features for unbalanced sample groups

Abstract Background To understand biology and differences among various tissues or cell types, one typically searches for molecular features that display characteristic abundance patterns. Several specificity metrics have been introduced to identify tissue-specific molecular features, but these eith...

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Bibliographic Details
Main Authors: Celine Everaert, Pieter-Jan Volders, Annelien Morlion, Olivier Thas, Pieter Mestdagh
Format: Article
Language:English
Published: BMC 2020-02-01
Series:BMC Bioinformatics
Subjects:
Specificity scoring
RNA-sequencing
GTEx
Online Access:http://link.springer.com/article/10.1186/s12859-020-3407-z

Internet

http://link.springer.com/article/10.1186/s12859-020-3407-z

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