ACx-projecting cholinergic neurons in the NB influence the BLA ensembles to modulate the discrimination of auditory fear memory

ACx-projecting cholinergic neurons in the NB influence the BLA ensembles to modulate the discrimination of auditory fear memory

Abstract Animals need discriminating auditory fear memory (DAFM) to survive, but the related neural circuits of DAFM remain largely unknown. Our study shows that DAFM depends on acetylcholine (ACh) signal in the auditory cortex (ACx), which is projected from the nucleus basalis (NB). At the encoding...

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Bibliographic Details
Main Authors: Yan Yan, Da Song, Yue Jin, Yujun Deng, Chunjian Wang, Tao Huang, Yuanhong Tang, Yu Yang, Yun Zhang, Zhe Wang, Zhifang Dong, Yuetian Wang, Juan Zhao, Junjun Ni, Hui Li, Jun Zhang, Yiran Lang, Yili Wu, Hong Qing, Zhenzhen Quan
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02384-8

Internet

https://doi.org/10.1038/s41398-023-02384-8

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