Discovery of a novel NUAK1 inhibitor against pancreatic cancer

The novel (nua) kinase family 1 (NUAK1) is an AMPK-related kinase and its expression is associated with tumor malignancy and poor prognosis in several types of cancer, suggesting its potential as a target for cancer therapy. Therefore, the development of NUAK1-targeting inhibitors could improve ther...

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Bibliographic Details
Main Authors: Myeong-Seong Seo, Kyung Hee Jung, Kewon Kim, Ji Eun Lee, Beom Seok Han, Soyeon Ko, Jae Ho Kim, Sungwoo Hong, So Ha Lee, Soon-Sun Hong
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222006308