Involvement of neuronal nitric oxide synthase in N-methyl-N-nitrosourea-induced retinal degeneration in mice

Involvement of neuronal nitric oxide synthase in N-methyl-N-nitrosourea-induced retinal degeneration in mice

N-methyl-N-nitrosourea (MNU) is widely used to study the mechanism of retinal degenerative diseases (RDs) because of its selectivity of photoreceptor cell death. Many reports suggest that excessive nitric oxide (NO) plays a crucial role in neuronal cell death. We hypothesized that nitric oxide synth...

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Bibliographic Details
Main Authors: Yoshiki Koriyama, Suguru Hisano, Kazuhiro Ogai, Kayo Sugitani, Ayako Furukawa, Satoru Kato
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Journal of Pharmacological Sciences
Subjects:
Neurotoxicity
Nitric oxide
Retina
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861315000407

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http://www.sciencedirect.com/science/article/pii/S1347861315000407

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