The Role and Mechanism of Pyroptosis and Potential Therapeutic Targets in Sepsis: A Review

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Recently was been found that pyroptosis is a unique form of proinflammatory programmed death, that is different from apoptosis. A growing number of studies have investigated pyroptosis and it...

Full description

Bibliographic Details
Main Authors: Xiangtao Zheng, Weiwei Chen, Fangchen Gong, Ying Chen, Erzhen Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.711939/full