Nuclear PTEN’s Functions in Suppressing Tumorigenesis: Implications for Rare Cancers

<i>Phosphatase and tensin homolog</i> (<i>PTEN</i>) encodes a tumor-suppressive phosphatase with both lipid and protein phosphatase activity. The tumor-suppressive functions of PTEN are lost through a variety of mechanisms across a wide spectrum of human malignancies, includi...

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Bibliographic Details
Main Author: Casey G. Langdon
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/13/2/259