Phenolic and flavonoid content and in vitro inhibitory effect of some Amazonian fruit juices on CYP3A4 activity

Phenolic and flavonoid content and in vitro inhibitory effect of some Amazonian fruit juices on CYP3A4 activity

ABSTRACT Many foods interact with drugs and may cause changes in the pharmacological effects of the co-administered therapeutic agent. The enzyme CYP3A4, which belongs to the cytochrome P450 enzyme complex, is responsible for the metabolism of most drugs currently on the market and is involved in ma...

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Bibliographic Details
Main Authors: Edna Márcia Almeida COSTA, Mariana Brasil DE ANDRADE FIGUEIRA, Daniel Blascke CARRÃO, Maísa Daniela HABENSCHUS, Anderson Rodrigo Moraes DE OLIVEIRA, Leonard Domingo Rosales ACHO, Emerson Silva LIMA, Igor Rafael DOS SANTOS MAGALHÃES
Format: Article
Language:English
Published: Instituto Nacional de Pesquisas da Amazônia 2022-07-01
Series:Acta Amazonica
Subjects:
edible plants
metabolism
enzyme inhibition
drug interactions
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672022000200172&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672022000200172&lng=en&tlng=en

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