RvD1<sub>n-3 DPA</sub> Downregulates the Transcription of Pro-Inflammatory Genes in Oral Epithelial Cells and Reverses Nuclear Translocation of Transcription Factor p65 after TNF-α Stimulation

RvD1<sub>n-3 DPA</sub> Downregulates the Transcription of Pro-Inflammatory Genes in Oral Epithelial Cells and Reverses Nuclear Translocation of Transcription Factor p65 after TNF-α Stimulation

Specialized pro-resolving mediators (SPMs) are multifunctional lipid mediators that participate in the resolution of inflammation. We have recently described that oral epithelial cells (OECs) express receptors of the SPM resolvin RvD1<sub>n-3 DPA</sub> and that cultured OECs respond to R...

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Bibliographic Details
Main Authors: Maria G. Balta, Olav Schreurs, Rashi Halder, Thomas M. Küntziger, Frank Saetre, Inger Johanne S. Blix, Espen S. Baekkevold, Enrico Glaab, Karl Schenck
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
resolvin
specialized pro-resolving mediators
oral epithelium
gingival
oral inflammation
periodontitis
Online Access:https://www.mdpi.com/1422-0067/23/23/14878

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https://www.mdpi.com/1422-0067/23/23/14878

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