Development and validation of a multiplex electrochemiluminescence immunoassay to evaluate dry eye disease in rat tear fluids
Abstract Dry eye disease (DED) is a challenge in ophthalmology. Rat models represent valuable tools to study the pathophysiology and to develop novel treatments. A major challenge in DED research is detecting multiple biomarkers in a low tear volume sample. Multiplex immunoassays for DED rat researc...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-39397-8 |