Astrocytic modulation of excitatory synaptic signaling in a mouse model of Rett syndrome

Studies linking mutations in Methyl CpG Binding Protein 2 (MeCP2) to physiological defects in the neurological disease, Rett syndrome, have focused largely upon neuronal dysfunction despite MeCP2 ubiquitous expression. Here we explore roles for astrocytes in neuronal network function using cortical...

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Bibliographic Details
Main Authors: Benjamin Rakela, Paul Brehm, Gail Mandel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/31629