Neuroimmune characterization of optineurin insufficiency mouse model during ageing

Neuroimmune characterization of optineurin insufficiency mouse model during ageing

Abstract Optineurin is a multifunctional polyubiquitin-binding protein implicated in inflammatory signalling. Optineurin mutations are associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), neurodegenerative diseases characterised by neuronal loss, neuroinflammation,...

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Bibliographic Details
Main Authors: Nikolina Mohovic, Josip Peradinovic, Andrea Markovinovic, Raffaello Cimbro, Zeljka Minic, Marin Dominovic, Hrvoje Jakovac, Jerneja Nimac, Boris Rogelj, Ivana Munitic
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38875-3

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https://doi.org/10.1038/s41598-023-38875-3

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