Association between circulating SerpinB1 levels and insulin sensitivity in Japanese with type 2 diabetes: A single-center, cross-sectional, observational study.

Association between circulating SerpinB1 levels and insulin sensitivity in Japanese with type 2 diabetes: A single-center, cross-sectional, observational study.

Plasma and liver SerpinB1 levels are elevated in mice with insulin resistance and promote β-cell proliferation in human islets. We measured serum SerpinB1 levels in Japanese subjects with or without type 2 diabetes (T2DM). We enrolled 12 normal glucose tolerance (NGT) and 51 T2DM subjects. There was...

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Bibliographic Details
Main Authors: Mayu Kyohara, Daisuke Miyashita, Ryota Inoue, Kuniyuki Nishiyama, Takahiro Tsuno, Tomoko Okuyama, Yu Togashi, Yasuo Terauchi, Jun Shirakawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0276915

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https://doi.org/10.1371/journal.pone.0276915

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