Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries

Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries

Abstract Background The functions and protein expressions of the blood–brain barrier are changed throughout brain development following birth. This study aimed to develop a method to isolate brain capillaries from a single frozen neonatal mouse brain and elucidate the enrichment of brain capillaries...

Full description

Bibliographic Details
Main Authors: Yudai Hamada, Seiryo Ogata, Takeshi Masuda, Shingo Ito, Sumio Ohtsuki
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Fluids and Barriers of the CNS
Subjects:
Brain capillaries
Isolation
Neonate
Proteomics
Single brain
Age
Online Access:https://doi.org/10.1186/s12987-023-00449-w

Internet

https://doi.org/10.1186/s12987-023-00449-w

Similar Items