Metabolomic Signatures in Doxorubicin-Induced Metabolites Characterization, Metabolic Inhibition, and Signaling Pathway Mechanisms in Colon Cancer HCT116 Cells

Metabolomic Signatures in Doxorubicin-Induced Metabolites Characterization, Metabolic Inhibition, and Signaling Pathway Mechanisms in Colon Cancer HCT116 Cells

Doxorubicin (DOX) is a chemotherapeutic agent is used for various cancer cells. To characterize the chemical structural components and metabolic inhibition, we applied a DOX to HCT116 colon cancer cells using an independent metabolites profiling approach. Chemical metabolomics has been involved in t...

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Bibliographic Details
Main Authors: Raja Ganesan, Vasantha-Srinivasan Prabhakaran, Abilash Valsala Gopalakrishnan
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Metabolites
Subjects:
HCT116 cells
doxorubicin
colorectal cancer
NMR
metabolomics
metabolic profiling
Online Access:https://www.mdpi.com/2218-1989/12/11/1047

Internet

https://www.mdpi.com/2218-1989/12/11/1047

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