Lin28A/CENPE Promoting the Proliferation and Chemoresistance of Acute Myeloid Leukemia

The prognosis of chemoresistant acute myeloid leukemia (AML) is still poor, mainly owing to the sustained proliferation ability of leukemic cells, while the microtubules have a major role in sustaining the continuity of cell cycle. In the present study, we have identified CENPE, a microtubular kines...

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Bibliographic Details
Main Authors: Mingyue Shi, Junwei Niu, Xiaona Niu, Honggang Guo, Yanliang Bai, Jie Shi, Weiya Li, Kai Sun, Yuqing Chen, Fengmin Shao
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.763232/full