Model‐based meta‐analysis of ethnic differences and their variabilities in clearance of oral drugs classified by clearance mechanism
Abstract In this study, the ethnic ratios (ERs) of oral clearance between Japanese and Western populations were subjected to model‐based meta‐analysis (MBMA) for 81 drugs evaluated in 673 clinical studies. The drugs were classified into eight groups according to the clearance mechanism, and the ER f...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-08-01
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| Series: | CPT: Pharmacometrics & Systems Pharmacology |
| Online Access: | https://doi.org/10.1002/psp4.12980 |