Model‐based meta‐analysis of ethnic differences and their variabilities in clearance of oral drugs classified by clearance mechanism
Abstract In this study, the ethnic ratios (ERs) of oral clearance between Japanese and Western populations were subjected to model‐based meta‐analysis (MBMA) for 81 drugs evaluated in 673 clinical studies. The drugs were classified into eight groups according to the clearance mechanism, and the ER f...
Main Authors: | Hiromi Sato, Rika Marutani, Ryota Takaoka, Daniel Mori‐Fegan, Xinying Wang, Kazuya Maeda, Hiroyuki Kusuhara, Hiroshi Suzuki, Hideki Yoshioka, Akihiro Hisaka |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2023-08-01
|
Series: | CPT: Pharmacometrics & Systems Pharmacology |
Online Access: | https://doi.org/10.1002/psp4.12980 |
Similar Items
-
Data‐driven disease progression model of Parkinson's disease and effect of sex and genetic variants
by: Ryota Jin, et al.
Published: (2024-04-01) -
Scores of Health-Related Quality of Life Questionnaire Worsen Consistently in Patients of COPD: Estimating Disease Progression over 30 Years by SReFT with Individual Data Collected in SUMMIT Trial
by: Shinya Kawamatsu, et al.
Published: (2020-08-01) -
Standardizing the measurement of parasite clearance in falciparum malaria: the parasite clearance estimator.
by: Flegg, J, et al.
Published: (2011) -
Global Comparison of Changes in the Number of Test-Positive Cases and Deaths by Coronavirus Infection (COVID-19) in the World
by: Akihiro Hisaka, et al.
Published: (2020-06-01) -
HIV clearance in infants.
by: McClure, M, et al.
Published: (1996)