Sarpogrelate hydrochloride ameliorates diabetic nephropathy associated with inhibition of macrophage activity and inflammatory reaction in db/db mice.

Sarpogrelate hydrochloride ameliorates diabetic nephropathy associated with inhibition of macrophage activity and inflammatory reaction in db/db mice.

The aim of this study was to evaluate the effects of sarpogrelate hydrochloride (SH), a selective serotonin 2A receptor antagonist, on diabetic nephropathy in a type 2 diabetes mouse model. We treated db/m and db/db mice with SH (30 mg/kg/day) for 12 weeks. Rat renal proximal tubule cells (NRK-52E)...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Eun Soo Lee, Mi Young Lee, Mi-Hye Kwon, Hong Min Kim, Jeong Suk Kang, You Mi Kim, Eun Young Lee, Choon Hee Chung
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	Public Library of Science (PLoS) 2017-01-01
Cyfres:	PLoS ONE
Mynediad Ar-lein:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0179221&type=printable

Eitemau Tebyg

EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation
gan: Kyung Bong Ha, et al.
Cyhoeddwyd: (2022-02-01)

Sodium Meta-Arsenite Ameliorates Hyperglycemia in Obese Diabetic db/db Mice by Inhibition of Hepatic Gluconeogenesis
gan: Young-Sun Lee, et al.
Cyhoeddwyd: (2014-01-01)

Chronic resveratrol treatment protects pancreatic islets against oxidative stress in db/db mice.
gan: Young-Eun Lee, et al.
Cyhoeddwyd: (2012-01-01)

Celastrol, an NF-κB inhibitor, improves insulin resistance and attenuates renal injury in db/db mice.
gan: Jung Eun Kim, et al.
Cyhoeddwyd: (2013-01-01)

<span style="font-variant: small-caps">d</span>-allulose Ameliorates Metabolic Dysfunction in C57BL/KsJ-db/db Mice
gan: Dayoun Lee, et al.
Cyhoeddwyd: (2020-08-01)

The Herbal Combination CPA4-1 Inhibits Changes in Retinal Capillaries and Reduction of Retinal Occludin in db/db Mice
gan: Young Sook Kim, et al.
Cyhoeddwyd: (2020-07-01)

Vascular endothelial growth factor-receptor 1 inhibition aggravates diabetic nephropathy through eNOS signaling pathway in db/db mice.
gan: Keun Suk Yang, et al.
Cyhoeddwyd: (2014-01-01)

Zuogui Wan ameliorates high glucose-induced podocyte apoptosis and improves diabetic nephropathy in db/db mice
gan: Bingbing Zhu, et al.
Cyhoeddwyd: (2022-11-01)

Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice
gan: Jeong-Won Kim, et al.
Cyhoeddwyd: (2024-07-01)

Therapeutic effects of fenofibrate on diabetic peripheral neuropathy by improving endothelial and neural survival in db/db mice.
gan: Ye Rim Cho, et al.
Cyhoeddwyd: (2014-01-01)

Beneficial Effects of Sarpogrelate and Rosuvastatin in High Fat Diet/Streptozotocin-Induced Nephropathy in Mice.
gan: Dong-Hyun Kim, et al.
Cyhoeddwyd: (2016-01-01)

Stevia (Stevia rebaudiana) extract ameliorates insulin resistance by regulating mitochondrial function and oxidative stress in the skeletal muscle of db/db mice
gan: Jin-Young Han, et al.
Cyhoeddwyd: (2023-07-01)

Pravastatin and Sarpogrelate Synergistically Ameliorate Atherosclerosis in LDLr-Knockout Mice.
gan: Kyung-Yeon Park, et al.
Cyhoeddwyd: (2016-01-01)

Silk Fibroin Promotes the Regeneration of Pancreatic β-Cells in the C57BL/KsJ-<i>Lepr<sup>db/db</sup></i> Mouse
gan: So-young Park, et al.
Cyhoeddwyd: (2020-07-01)

Fenofibrate improves renal lipotoxicity through activation of AMPK-PGC-1α in db/db mice.
gan: Yu Ah Hong, et al.
Cyhoeddwyd: (2014-01-01)

Irbesartan Ameliorates Diabetic Nephropathy by Suppressing the RANKL-RANK-NF-κB Pathway in Type 2 Diabetic db/db Mice
gan: Xiao-Wen Chen, et al.
Cyhoeddwyd: (2016-01-01)

Polydatin Alleviates Diabetes-Induced Hyposalivation through Anti-Glycation Activity in db/db Mouse
gan: Hyung Rae Kim, et al.
Cyhoeddwyd: (2021-12-01)

M2 macrophage infusion ameliorates diabetic glomerulopathy via the JAK2/STAT3 pathway in db/db mice
gan: Yulin Gu, et al.
Cyhoeddwyd: (2024-12-01)

Corrigendum to “Irbesartan Ameliorates Diabetic Nephropathy by Suppressing the RANKL-RANK-NF-κB Pathway in Type 2 Diabetic db/db Mice”
gan: Xiao-Wen Chen, et al.
Cyhoeddwyd: (2016-01-01)

Anti-Diabetic Effects of <i>Allium hookeri</i> Extracts Prepared by Different Methods in Type 2 C57BL/J-<i>db/db</i> Mice
gan: Ji-Hye Choi, et al.
Cyhoeddwyd: (2022-04-01)

Anti-diabetic effect of black ginseng extract by augmentation of AMPK protein activity and upregulation of GLUT2 and GLUT4 expression in db/db mice
gan: Ok-Hwa Kang, et al.
Cyhoeddwyd: (2017-06-01)

Cudrania tricuspidata water extract improved obesity-induced hepatic insulin resistance in db/db mice by suppressing ER stress and inflammation
gan: Ok-Kyung Kim, et al.
Cyhoeddwyd: (2015-10-01)

Antioxidative and antidiabetic effects of germinated rough rice extract in 3T3-L1 adipocytes and C57BLKS/J-db/db mice
gan: Youn Ri Lee, et al.
Cyhoeddwyd: (2019-11-01)

Qihu Preparation Ameliorates Diabetes by Activating the AMPK Signaling Pathway in db/db Mice
gan: Zeng H, et al.
Cyhoeddwyd: (2021-07-01)

Crocin ameliorates hepatic steatosis through activation of AMPK signaling in db/db mice
gan: Li Luo, et al.
Cyhoeddwyd: (2019-01-01)

Supplementary Effects of <i>Allium hookeri</i> Extract on Glucose Tolerance in Prediabetic Subjects and C57BL/KsJ-<i>db/db</i> Mice
gan: Ji-Su Kim, et al.
Cyhoeddwyd: (2023-09-01)

Trametenolic Acid Ameliorates the Progression of Diabetic Nephropathy in db/db Mice via Nrf2/HO-1 and NF-κB-Mediated Pathways
gan: Qi Duan, et al.
Cyhoeddwyd: (2022-01-01)

Therapeutic Effects of Tangshen Formula on Diabetic Nephropathy in db/db Mice Using Cytokine Antibody Array
gan: Xue Mei Fan, et al.
Cyhoeddwyd: (2018-01-01)

(-)-Gallocatechin Gallate Mitigates Metabolic Syndrome-Associated Diabetic Nephropathy in <i>db/db</i> Mice
gan: Xin Xiao, et al.
Cyhoeddwyd: (2024-06-01)

Unraveling the superiority of (−)‐gallocatechin gallate to (−)‐epigallocatechin‐3‐gallate in protection of diabetic nephropathy of db/db mice
gan: Xin Xiao, et al.
Cyhoeddwyd: (2024-03-01)

Polysaccharides of Floccularia luteovirens Alleviate Oxidative Damage and Inflammatory Parameters of Diabetic Nephropathy in db/db Mice
gan: Huan Wang, et al.
Cyhoeddwyd: (2023-04-01)

Astragalus–Saffron–Rhubarb Mixture Delays the Progress of Diabetic Nephropathy in db/db Mice
gan: Zhou XC, et al.
Cyhoeddwyd: (2021-12-01)

Evogliptin, a DPP-4 inhibitor, prevents diabetic cardiomyopathy by alleviating cardiac lipotoxicity in db/db mice
gan: Trong Kha Pham, et al.
Cyhoeddwyd: (2023-04-01)

α-Mangostin ameliorates hepatic steatosis and insulin resistance by inhibition C-C chemokine receptor 2.
gan: Hong Min Kim, et al.
Cyhoeddwyd: (2017-01-01)

Effect of Korean Red Ginseng through comparative analysis of cardiac gene expression in db/db mice
gan: Young-Jin Jang, et al.
Cyhoeddwyd: (2021-05-01)

<i>Ishige okamurae</i> Extract Ameliorates the Hyperglycemia and Body Weight Gain of <i>db/db</i> Mice through Regulation of the PI3K/Akt Pathway and Thermogenic Factors by FGF21
gan: Young-Jin Seo, et al.
Cyhoeddwyd: (2019-07-01)

Salvianolic Acid B Ameliorates Hyperglycemia and Dyslipidemia in db/db Mice through the AMPK Pathway
gan: Ming-Qing Huang, et al.
Cyhoeddwyd: (2016-12-01)

Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice
gan: Xue M, et al.
Cyhoeddwyd: (2015-08-01)

Olmesartan Medoxomil, An Angiotensin II-Receptor Blocker, Ameliorates Renal Injury In db/db Mice
gan: Zhu Y, et al.
Cyhoeddwyd: (2019-10-01)

Ferulic acid targets ACSL1 to ameliorate lipid metabolic disorders in db/db mice
gan: Jie Gao, et al.
Cyhoeddwyd: (2022-04-01)