Complement Inhibitors Vitronectin and Clusterin Are Recruited from Human Serum to the Surface of Coronavirus OC43-Infected Lung Cells through Antibody-Dependent Mechanisms

Little is known about the role of complement (C’) in infections with highly prevalent circulating human coronaviruses such as OC43, a group of viruses of major public health concern. Treatment of OC43-infected human lung cells with human serum resulted in C3 deposition on their surfaces and generati...

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Bibliographic Details
Main Authors: Candace R. Fox, Griffith D. Parks
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/1/29