Circulating immune complexes and mutations of HBsAg are associated with the undetectable HBsAg in anti-HBs and HBeAg positive occult hepatitis B virus infection

Circulating immune complexes and mutations of HBsAg are associated with the undetectable HBsAg in anti-HBs and HBeAg positive occult hepatitis B virus infection

IntroductionOccult hepatitis B virus infection (OBI) is an HBsAg negative state in HBV infection with usually inactive HBV replication. However, there were a minority of individuals with positive HBeAg and anti-HBs among OBI blood donors and few studies have focused on this unusual serological patte...

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Bibliographic Details
Main Authors: Ying Yan, Huizhen Sun, Le Chang, Huimin Ji, Xinyi Jiang, Shi Song, Yingzi Xiao, Kaihao Feng, Abudulimutailipu Nuermaimaiti, Zhuoqun Lu, Lunan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Microbiology
Subjects:
occult HBV infection
circulating immune complexes
immune escape mutations
Lumipulse HBsAg-HQ assay
HBeAg
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1063616/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1063616/full

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