Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies

Detecting copy number status and uncovering subclonal markers in heterogeneous tumor biopsies

<p>Abstract</p> <p>Background</p> <p>Genomic aberrations can be used to determine cancer diagnosis and prognosis. Clinically relevant novel aberrations can be discovered using high-throughput assays such as Single Nucleotide Polymorphism (SNP) arrays and next-generation...

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Bibliographic Details
Main Authors: Xu Fang, Cheng Elaine, Hoyt Kathleen, Bacchiocchi Antonella, Narayan Deepak, Ariyan Stephan, Parisi Fabio, Li Peining, Halaban Ruth, Kluger Yuval
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Genomics
Subjects:
copy number
SNP arrays
Next generation sequencing
melanoma
Online Access:http://www.biomedcentral.com/1471-2164/12/230

Internet

http://www.biomedcentral.com/1471-2164/12/230

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