Interactions of the Kv1.1 Channel with Peptide Pore Blockers: A Fluorescent Analysis on Mammalian Cells

Interactions of the Kv1.1 Channel with Peptide Pore Blockers: A Fluorescent Analysis on Mammalian Cells

The voltage-gated potassium channel Kv1.1, which is abundant in the CNS and peripheral nervous system, controls neuronal excitability and neuromuscular transmission and mediates a number of physiological functions in non-excitable cells. The development of some diseases is accompanied by changes in...

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Bibliographic Details
Main Authors: Nikita A. Orlov, Elena V. Kryukova, Anastasia V. Efremenko, Sergey A. Yakimov, Victoria A. Toporova, Mikhail P. Kirpichnikov, Oksana V. Nekrasova, Alexey V. Feofanov
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Membranes
Subjects:
Kv1.1 channel
pore blocker
fluorescence
confocal
patch clamp
affinity
Online Access:https://www.mdpi.com/2077-0375/13/7/645

Internet

https://www.mdpi.com/2077-0375/13/7/645

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