Discovery of Small Molecules That Target Vascular Endothelial Growth Factor Receptor-2 Signalling Pathway Employing Molecular Modelling Studies

Discovery of Small Molecules That Target Vascular Endothelial Growth Factor Receptor-2 Signalling Pathway Employing Molecular Modelling Studies

Angiogenesis is defined as the formation of new blood vessels and is a key phenomenon manifested in a host of cancers during which tyrosine kinases play a crucial role. Vascular endothelial growth factor receptor-2 (VEGFR-2) is pivotal in cancer angiogenesis, which warrants the urgency of discoverin...

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Bibliographic Details
Main Authors: Shailima Rampogu, Ayoung Baek, Chanin Park, Minky Son, Shraddha Parate, Saravanan Parameswaran, Yohan Park, Baji Shaik, Ju Hyun Kim, Seok Ju Park, Keun Woo Lee
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
anti-angiogenic inhibitors
type-II anti-angiogenic inhibitors
VEGFR-2
natural products
protein kinase inhibitors
Online Access:https://www.mdpi.com/2073-4409/8/3/269

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https://www.mdpi.com/2073-4409/8/3/269

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