Apixaban for treatment of confirmed heparin-induced thrombocytopenia: a case report and review of literature

Apixaban for treatment of confirmed heparin-induced thrombocytopenia: a case report and review of literature

Abstract Background Heparin-induced thrombocytopenia (HIT) is a life and limb-threatening condition caused by the binding of platelet-activating antibodies (IgG) to multimolecular platelet factor 4 (PF4)/heparin complexes because of heparin exposure. The by-product of this interaction is thrombin fo...

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Bibliographic Details
Main Authors: Daniel E. Ezekwudo, Rebecca Chacko, Bolanle Gbadamosi, Syeda Batool, Sussana Gaikazian, Theodore E. Warkentin, Jo-Ann I. Sheppard, Ishmael Jaiyesimi
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Experimental Hematology & Oncology
Subjects:
Heparin-induced thrombocytopenia
Serotonin-release assay
Platelet factor 4
Direct oral anticoagulants
Argatroban
Apixaban
Online Access:http://link.springer.com/article/10.1186/s40164-017-0080-7

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http://link.springer.com/article/10.1186/s40164-017-0080-7

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