Th2 Cytokines Affect the Innate Immune Barrier without Impairing the Physical Barrier in a 3D Model of Normal Human Skin

Th2 Cytokines Affect the Innate Immune Barrier without Impairing the Physical Barrier in a 3D Model of Normal Human Skin

(1) Background: Atopic dermatitis is one of the most common inflammatory skin diseases characterized by T helper (Th) 2 and Th22 cells producing interleukin (IL)-4/IL-13 and IL-22, respectively. The specific contribution of each cytokine to the impairment of the physical and the immune barrier via T...

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Bibliographic Details
Main Authors: Elena Donetti, Federica Riva, Serena Indino, Giulia Lombardo, Franz Baruffaldi Preis, Elia Rosi, Francesca Prignano
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Journal of Clinical Medicine
Subjects:
human epidermis
immunofluorescence
transmission electron microscopy
keratinocytes
interleukins
toll-like receptors
Online Access:https://www.mdpi.com/2077-0383/12/5/1941

Internet

https://www.mdpi.com/2077-0383/12/5/1941

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