The loss of neoantigens is an important reason for immune escape in multiple myeloma patients with high intratumor heterogeneity
Abstract Objectives Intratumor heterogeneity (ITH) is an important factor for clinical outcomes in patients with multiple myeloma (MM). High ITH has been proven to be a key reason for tumor immune escape and treatment resistance. Neoantigens are thought to be associated with ITH, but the specific co...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-12-01
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Series: | Cancer Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/cam4.6721 |