The loss of neoantigens is an important reason for immune escape in multiple myeloma patients with high intratumor heterogeneity

Abstract Objectives Intratumor heterogeneity (ITH) is an important factor for clinical outcomes in patients with multiple myeloma (MM). High ITH has been proven to be a key reason for tumor immune escape and treatment resistance. Neoantigens are thought to be associated with ITH, but the specific co...

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Bibliographic Details
Main Authors: Yue Wang, Jiadai Xu, Tianwei Lan, Chi Zhou, Peng Liu
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.6721