Network Diffusion Model of Progression Predicts Longitudinal Patterns of Atrophy and Metabolism in Alzheimer’s Disease

Network Diffusion Model of Progression Predicts Longitudinal Patterns of Atrophy and Metabolism in Alzheimer’s Disease

Alzheimer’s disease pathology (AD) originates in the hippocampus and subsequently spreads to temporal, parietal, and prefrontal association cortices in a relatively stereotyped progression. Current evidence attributes this orderly progression to transneuronal transmission of misfolded proteins along...

Full description

Bibliographic Details
Main Authors: Ashish Raj, Eve LoCastro, Amy Kuceyeski, Duygu Tosun, Norman Relkin, Michael Weiner
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714010638

Internet

http://www.sciencedirect.com/science/article/pii/S2211124714010638

Similar Items