The healing of bone defects by cell-free and stem cell-seeded 3D-printed PLA tissue-engineered scaffolds

Abstract In this paper, the in-vivo healing of critical-sized bony defects by cell-free and stem cell-seeded 3D-printed PLA scaffolds was studied in rat calvaria bone. The scaffolds were implanted in the provided defect sites and histological analysis was conducted after 8 and 12 weeks. The results...

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Bibliographic Details
Main Authors: Marjan Bahraminasab, Athar Talebi, Nesa Doostmohammadi, Samaneh Arab, Ali Ghanbari, Sam Zarbakhsh
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:https://doi.org/10.1186/s13018-022-03213-2