Cajanolactone A from Cajanus cajan Promoted Osteoblast Differentiation in Human Bone Marrow Mesenchymal Stem Cells via Stimulating Wnt/LRP5/β-Catenin Signaling

Cajanolactone A from Cajanus cajan Promoted Osteoblast Differentiation in Human Bone Marrow Mesenchymal Stem Cells via Stimulating Wnt/LRP5/β-Catenin Signaling

Cajanolactone A (CLA) is a stilbenoid discovered by us from Cajanus cajan (L.) Millsp. In our study, CLA was found to promote osteoblast differentiation in human bone marrow mesenchymal stem cells (hBMSCs), as judged by increased cellular alkaline phosphatase activity and extracellular calcium depos...

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Bibliographic Details
Main Authors: Shan Liu, Zhuo-Hui Luo, Gui-Mei Ji, Wei Guo, Jia-Zhong Cai, Lin-Chun Fu, Juan Zhou, Ying-Jie Hu, Xiao-Ling Shen
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
cajanolactone A
Cajanus cajan (L.) Millsp.
osteoblast differentiation
Wnt/β-catenin signaling pathway
Online Access:http://www.mdpi.com/1420-3049/24/2/271

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http://www.mdpi.com/1420-3049/24/2/271

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