Hepatocyte growth factor-mediated apoptosis mechanisms of cytotoxic CD8+ T cells in normal and cirrhotic livers

Hepatocyte growth factor-mediated apoptosis mechanisms of cytotoxic CD8+ T cells in normal and cirrhotic livers

Abstract Intrahepatic stem/progenitor cells and cytotoxic CD8+ T cells (CD8+ T cells) in the cirrhotic liver undergo apoptosis, which potentially facilitates progression to cancer. Here, we report that hepatocyte growth factor (HGF) signaling plays an important role in promoting normal and damaged l...

Full description

Bibliographic Details
Main Authors: Quanyu Chen, Min Yan, Heng Lin, Jiejuan Lai, Zhiqing Yang, Deyu Hu, Yuanyu Deng, Saiyu Shi, Ling Shuai, Leida Zhang, Hongyu Zhang, Lianhua Bai
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01313-4

Internet

https://doi.org/10.1038/s41420-023-01313-4

Similar Items