Novel therapeutic agents for HbF induction: a new era for treatment of β thalassemia?
<p>Fetal globin is endogenous, normally integrated in hematopoietic stem cells in all humans, and available for reactivation. Inducing expression of fetal globin (g-globin) gene expression to 60-70% of a globin synthesis produces β-thalassemia trait globin synthetic ratios, and has be...
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| Format: | Article |
| Language: | English |
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MDPI AG
2011-12-01
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| Series: | Thalassemia Reports |
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| Online Access: | http://www.pagepressjournals.org/index.php/thal/article/view/297 |