Deletions of the Plasmodium falciparum histidine-rich protein 2/3 genes are common in field isolates from north-eastern Tanzania

Abstract Plasmodium falciparum parasites lacking histidine-rich protein 2 and 3 (pfhrp2/3) genes have been reported in several parts of the world. These deletions are known to compromise the effectiveness of HRP2-based malaria rapid diagnostic tests (HRP2-RDT). The National Malaria Control Programme...

Full description

Bibliographic Details
Main Authors: Robert D. Kaaya, Reginald A. Kavishe, Filemon F. Tenu, Johnson J. Matowo, Franklin W. Mosha, Chris Drakeley, Colin J. Sutherland, Khalid B. Beshir
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-09878-3