Memantine for Multiple Sclerosis: A Systematic Review and Meta-Analysis of Randomized Trials

Background: Multiple sclerosis (MS), a disabling demyelinating disease of the central nervous system, is associated with cognitive impairment, spasticity, and fatigue. There are still no established guidelines on the management of MS-related sequela. Memantine has the potential to reduce glutamate t...

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Bibliographic Details
Main Authors: Christian Wilson R. Turalde, Adrian I. Espiritu, Veeda Michelle M. Anlacan
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neurology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2020.574748/full