Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy

Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy

This review discusses various issues to consider when developing standard operating procedures for pre-clinical studies in the mdx mouse model of Duchenne muscular dystrophy (DMD). The review describes and evaluates a wide range of techniques used to measure parameters of muscle pathology in mdx mic...

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Bibliographic Details
Main Authors: Miranda D. Grounds, Hannah G. Radley, Gordon S. Lynch, Kanneboyina Nagaraju, Annamaria De Luca
Format: Article
Language:English
Published: Elsevier 2008-07-01
Series:Neurobiology of Disease
Subjects:
Mdx mouse
Muscular dystrophy
Standard operating procedures
Biological variation
Muscle function
Pre-clinical trials
Online Access:http://www.sciencedirect.com/science/article/pii/S096999610800065X

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http://www.sciencedirect.com/science/article/pii/S096999610800065X

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