<sup>225</sup>Ac-rHDL Nanoparticles: A Potential Agent for Targeted Alpha-Particle Therapy of Tumors Overexpressing SR-BI Proteins

<sup>225</sup>Ac-rHDL Nanoparticles: A Potential Agent for Targeted Alpha-Particle Therapy of Tumors Overexpressing SR-BI Proteins

Actinium-225 and other alpha-particle-emitting radionuclides have shown high potential for cancer treatment. Reconstituted high-density lipoproteins (rHDL) specifically recognize the scavenger receptor B type I (SR-BI) overexpressed in several types of cancer cells. Furthermore, after rHDL-SR-BI rec...

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Bibliographic Details
Main Authors: Tania Hernández-Jiménez, Guillermina Ferro-Flores, Enrique Morales-Ávila, Keila Isaac-Olivé, Blanca Ocampo-García, Liliana Aranda-Lara, Clara Santos-Cuevas, Myrna Luna-Gutiérrez, Laura De Nardo, Antonio Rosato, Laura Meléndez-Alafort
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
scavenger receptor B type I
reconstituted high-density lipoproteins
actinium-225
<sup>225</sup>Ac-rHDL
targeted alpha-particle therapy
Online Access:https://www.mdpi.com/1420-3049/27/7/2156

Internet

https://www.mdpi.com/1420-3049/27/7/2156

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