A Short Peptide Inhibitor as an Activity-Based Probe for Matriptase-2

Matriptase-2 is a type II transmembrane serine protease and a key regulator of systemic iron homeostasis. Since the activation mechanism and several features of the physiological role of matriptase-2 are not fully understood, there is strong need for analytical tools to perform tasks such as disting...

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Bibliographic Details
Main Authors: Martin Mangold, Michael Gütschow, Marit Stirnberg
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Pharmaceuticals
Subjects:
Online Access:http://www.mdpi.com/1424-8247/11/2/49