Dihydropyrimidinase-Related Protein 2 Is a New Partner in the Binding between 4E-BP2 and eIF4E Related to Neuronal Death after Cerebral Ischemia

Dihydropyrimidinase-Related Protein 2 Is a New Partner in the Binding between 4E-BP2 and eIF4E Related to Neuronal Death after Cerebral Ischemia

Transient cerebral ischemia induces neuronal degeneration, followed in time by secondary delayed neuronal death that is strongly correlated with a permanent inhibition of protein synthesis in vulnerable brain regions, while protein translational rates are recovered in resistant areas. In the transla...

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Bibliographic Details
Main Authors: Emma Martínez-Alonso, Alejandro Escobar-Peso, Natalia Guerra-Pérez, Marcel Roca, Jaime Masjuan, Alberto Alcázar
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
cerebral ischemia
eIF4E-binding protein
eIF4E
collapsing-response mediator protein 2
dihydropyrimidinase-related protein 2
protein phosphorylation
Online Access:https://www.mdpi.com/1422-0067/24/9/8246

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https://www.mdpi.com/1422-0067/24/9/8246

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