The antimicrobial peptide LI14 combats multidrug-resistant bacterial infections

A synthetic peptide LI14 demonstrates potent antibacterial activity against drug-resistant bacteria in vitro and in vivo by inducing membrane damage and disrupting membrane potential leading to metabolic perturbation.

Bibliographic Details
Main Authors: Jingru Shi, Chen Chen, Dejuan Wang, Zhiqiang Wang, Yuan Liu
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03899-4