Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s disease

Inhibition of Rac1-dependent forgetting alleviates memory deficits in animal models of Alzheimer’s disease

Abstract Accelerated forgetting has been identified as a feature of Alzheimer’s disease (AD), but the therapeutic efficacy of the manipulation of biological mechanisms of forgetting has not been assessed in AD animal models. Ras-related C3 botulinum toxin substrate 1 (Rac1), a small GTPase, has been...

詳細記述

書誌詳細
主要な著者: Wenjuan Wu, Shuwen Du, Wei Shi, Yunlong Liu, Ying Hu, Zuolei Xie, Xinsheng Yao, Zhenyu Liu, Weiwei Ma, Lin Xu, Chao Ma, Yi Zhong
フォーマット: 論文
言語:English
出版事項: Oxford University Press 2019-07-01
シリーズ:Protein & Cell
主題:
Alzheimer’s disease
Rac1
forgetting
memory loss
hippocampus
オンライン･アクセス:http://link.springer.com/article/10.1007/s13238-019-0641-0

インターネット

http://link.springer.com/article/10.1007/s13238-019-0641-0

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