Preparation of 6-Mercaptopurine Loaded Liposomal Formulation for Enhanced Cytotoxic Response in Cancer Cells

Preparation of 6-Mercaptopurine Loaded Liposomal Formulation for Enhanced Cytotoxic Response in Cancer Cells

6-Mercaptopurine (6-MP) is a well-known immunosuppressive medication with proven anti-proliferative activities. 6-MP possesses incomplete and highly variable oral absorption due to its poor water solubility, which might reduce its anti-cancer properties. To overcome these negative effects, we develo...

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Bibliographic Details
Main Authors: Alam Jamal, Amer H. Asseri, Ehab M. M. Ali, Afnan H. El-Gowily, Mohamed Imran Khan, Salman Hosawi, Reem Alsolami, Tarek A. Ahmed
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Nanomaterials
Subjects:
6-mercaptopurine
liposomes
human cell lines
IC<sub>50</sub>
apoptosis
cell cycle phases
Online Access:https://www.mdpi.com/2079-4991/12/22/4029

Internet

https://www.mdpi.com/2079-4991/12/22/4029

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