Phenotypic Evidence of T Cell Exhaustion and Senescence During Symptomatic Plasmodium falciparum Malaria

Phenotypic Evidence of T Cell Exhaustion and Senescence During Symptomatic Plasmodium falciparum Malaria

T cells play significant roles during Plasmodium falciparum infections. Their regulation of the immune response in symptomatic children with malaria has been deemed necessary to prevent immune associated pathology. In this study, we phenotypically characterized the expression of T cell inhibitory(PD...

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Bibliographic Details
Main Authors: Augustina Frimpong, Kwadwo Asamoah Kusi, Dennis Adu-Gyasi, Jones Amponsah, Michael Fokuo Ofori, Wilfred Ndifon
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
malaria
Plasmodium falciparum
T-cell
exhaustion
immune senescence
PD-1
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01345/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01345/full

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